{"id":11420,"date":"2024-07-09T06:46:41","date_gmt":"2024-07-09T06:46:41","guid":{"rendered":"https:\/\/4pal.net\/?p=11420"},"modified":"2024-07-05T07:06:28","modified_gmt":"2024-07-05T07:06:28","slug":"benh-mau-kho-dong-hemophilia-va-xet-nghiem-chan-doan","status":"publish","type":"post","link":"https:\/\/4pal.net\/benh-mau-kho-dong-hemophilia-va-xet-nghiem-chan-doan\/","title":{"rendered":"B\u1ec6NH M\u00c1U KH\u00d3 \u0110\u00d4NG (HEMOPHILIA) V\u00c0 X\u00c9T NGHI\u1ec6M CH\u1ea8N \u0110O\u00c1N"},"content":{"rendered":"<p>T\u1ea1i Vi\u1ec7t Nam, \u01b0\u1edbc t\u00ednh c\u00f3 tr\u00ean 6.200 ng\u01b0\u1eddi m\u1eafc hemophilia (b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng) v\u00e0 c\u00f3 kho\u1ea3ng tr\u00ean 60% ng\u01b0\u1eddi b\u1ec7nh \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb.<\/p>\n<h2><strong>\u00a0 B\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng (Hemophilia) l\u00e0 g\u00ec?<\/strong><\/h2>\n<ul>\n<li style=\"text-align: justify;\">Hemophilia l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u do nguy\u00ean nh\u00e2n di truy\u1ec1n (t\u1eeb cha m\u1eb9 truy\u1ec1n l\u1ea1i \u0111\u1eddi sau). B\u1ec7nh nh\u00e2n d\u1ec5 b\u1ecb ch\u1ea3y m\u00e1u kh\u00f3 c\u1ea7m v\u00ec thi\u1ebfu h\u1ee5t y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u.<\/li>\n<li style=\"text-align: justify;\">C\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u c\u00f3 s\u1eb5n trong th\u00e0nh ph\u1ea7n huy\u1ebft t\u01b0\u01a1ng c\u1ee7a m\u00e1u, khi m\u1ea1ch m\u00e1u v\u1ee1, c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t s\u1ebd t\u1ea1o m\u1ed9t chu\u1ed7i ph\u1ea3n \u1ee9ng \u0111\u1ec3 t\u1ea1o ra c\u1ee5c m\u00e1u \u0111\u00f4ng b\u00edt k\u00edn ch\u1ed7 v\u1ee1 c\u1ee7a m\u1ea1ch m\u00e1u ng\u0103n ch\u1ea3y m\u00e1u.<\/li>\n<li style=\"text-align: justify;\">C\u00f3 2 th\u1ec3 b\u1ec7nh: Hemophilia A &#8211; thi\u1ebfu y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u VIII, Hemophilia B &#8211; thi\u1ebfu y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u IX.<\/li>\n<li style=\"text-align: justify;\">M\u1ed9t khi mang thai, ng\u01b0\u1eddi m\u1eb9 mang gen Hemophilia c\u00f3 kh\u1ea3 n\u0103ng truy\u1ec1n gen cho \u0111\u1eddi sau. Trong tr\u01b0\u1eddng h\u1ee3p, n\u1ebfu gen X mang b\u1ec7nh truy\u1ec1n cho con trai th\u00ec con trai s\u1ebd b\u1ecb Hemophilia. N\u1ebfu truy\u1ec1n cho con g\u00e1i th\u00ec con g\u00e1i s\u1ebd mang gen Hemophilia.<\/li>\n<\/ul>\n<div id=\"attachment_11421\" style=\"width: 610px\" class=\"wp-caption alignnone\"><img fetchpriority=\"high\" decoding=\"async\" aria-describedby=\"caption-attachment-11421\" class=\"size-full wp-image-11421\" src=\"https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/BENH-MAU-KHO-DONG-HEMOPHILIA-VA-XET-NGHIEM-CHAN-DOAN.png\" alt=\"\" width=\"600\" height=\"337\" srcset=\"https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/BENH-MAU-KHO-DONG-HEMOPHILIA-VA-XET-NGHIEM-CHAN-DOAN.png 600w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/BENH-MAU-KHO-DONG-HEMOPHILIA-VA-XET-NGHIEM-CHAN-DOAN-300x169.png 300w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/BENH-MAU-KHO-DONG-HEMOPHILIA-VA-XET-NGHIEM-CHAN-DOAN-320x180.png 320w\" sizes=\"(max-width: 600px) 100vw, 600px\" \/><p id=\"caption-attachment-11421\" class=\"wp-caption-text\"><strong>C\u01a1 ch\u1ebf di truy\u1ec1n b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng khi mang thai \u2013 Vi\u1ec7n c\u00f4ng ngh\u1ec7 DNA<\/strong><\/p><\/div>\n<h2 style=\"text-align: justify;\"><strong>Bi\u1ec3u hi\u1ec7n b\u1ec7nh<\/strong>:<\/h2>\n<ul style=\"text-align: justify;\">\n<li style=\"text-align: justify;\">Ng\u01b0\u1eddi b\u1ec7nh r\u1ea5t d\u1ec5 b\u1ecb ch\u1ea3y m\u00e1u do va ch\u1ea1m, ch\u1ea5n th\u01b0\u01a1ng ho\u1eb7c c\u00f3 th\u1ec3 ch\u1ea3y m\u00e1u t\u1ef1 nhi\u00ean. C\u00f3 th\u1ec3 ch\u1ea3y m\u00e1u \u1edf b\u1ea5t k\u1ef3 c\u01a1 quan n\u00e0o trong c\u01a1 th\u1ec3 nh\u01b0ng th\u01b0\u1eddng g\u1eb7p nh\u1ea5t l\u00e0 c\u01a1 v\u00e0 kh\u1edbp<\/li>\n<\/ul>\n<p style=\"text-align: justify;\">Ch\u1ea3y m\u00e1u trong c\u01a1, kh\u1edbp, th\u01b0\u1eddng g\u1eb7p nh\u1ea5t l\u00e0 g\u1ed1i, khu\u1ef7u, \u0111\u1ea7u g\u1ed1i, m\u1eaft c\u00e1 ch\u00e2n, h\u00f4ng l\u01b0ng, c\u01a1 th\u1eaft l\u01b0ng, c\u01a1 b\u1eafp ch\u00e2n g\u00e2y ra \u0111au, s\u01b0ng c\u1ee9ng v\u00e0 kh\u00f3 c\u1eed \u0111\u1ed9ng kh\u1edbp.<\/p>\n<ul>\n<li style=\"text-align: justify;\">N\u1ebfu b\u1ec7nh di\u1ec5n ti\u1ebfn l\u00e2u, c\u00f3 th\u1ec3 \u0111\u1ec3 l\u1ea1i di ch\u1ee9ng bi\u1ebfn d\u1ea1ng kh\u1edbp, gi\u1edbi h\u1ea1n v\u1eadn \u0111\u1ed9ng.<\/li>\n<\/ul>\n<div id=\"attachment_11422\" style=\"width: 660px\" class=\"wp-caption alignnone\"><img decoding=\"async\" aria-describedby=\"caption-attachment-11422\" class=\"size-full wp-image-11422\" src=\"https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/Bao-cao-Tiep-can-dieu-tri-benh-nhan-Hemophilia-theo-huong-ca-the-hoa-cua-BS-Nguyen-Minh-Tuan.png\" alt=\"\" width=\"650\" height=\"419\" srcset=\"https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/Bao-cao-Tiep-can-dieu-tri-benh-nhan-Hemophilia-theo-huong-ca-the-hoa-cua-BS-Nguyen-Minh-Tuan.png 650w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2024\/07\/Bao-cao-Tiep-can-dieu-tri-benh-nhan-Hemophilia-theo-huong-ca-the-hoa-cua-BS-Nguyen-Minh-Tuan-300x193.png 300w\" sizes=\"(max-width: 650px) 100vw, 650px\" \/><p id=\"caption-attachment-11422\" class=\"wp-caption-text\"><strong>H\u1eadu qu\u1ea3 c\u1ee7a ch\u1ea3y m\u00e1u \u1edf ng\u01b0\u1eddi b\u1ec7nh Hemophilia<\/strong><\/p><\/div>\n<p>B\u00e1o c\u00e1o \u201c<em>Ti\u1ebfp c\u1eadn \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n Hemophilia theo h\u01b0\u1edbng c\u00e1 th\u1ec3 h\u00f3a<\/em>\u201d c\u1ee7a BS Nguy\u1ec5n Minh Tu\u1ea5n \u2013 Tr\u01b0\u1edfng khoa S\u1ed1t xu\u1ea5t huy\u1ebft, B\u1ec7nh vi\u1ec7n Nhi \u0111\u1ed3ng 1 t\u1ea1i Ch\u01b0\u01a1ng tr\u00ecnh h\u1ed9i th\u1ea3o khoa h\u1ecdc tr\u1ef1c tuy\u1ebfn nh\u1eb1m c\u1eadp nh\u1eadt ki\u1ebfn th\u1ee9c v\u00e0 trao \u0111\u1ed5i chuy\u00ean m\u00f4n trong c\u00f4ng t\u00e1c ch\u1ea9n \u0111o\u00e1n v\u00e0 qu\u1ea3n l\u00fd b\u1ec7nh nh\u00e2n Hemophilia n\u0103m 2023.<\/p>\n<h2>\u00a0\u00a0 <strong>C\u00e1c x\u00e9t nghi\u1ec7m \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh hemophilia<\/strong><\/h2>\n<p style=\"text-align: justify;\">Hi\u1ec7n t\u1ea1i, c\u00f3 hai lo\u1ea1i ch\u1ea9n \u0111o\u00e1n ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh xem m\u1ed9t ng\u01b0\u1eddi c\u00f3 ph\u1ea3i l\u00e0 ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh hay kh\u00f4ng: x\u00e9t nghi\u1ec7m \u0111\u00f4ng m\u00e1u \u0111\u1ec3 \u0111o ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u v\u00e0 x\u00e9t nghi\u1ec7m di truy\u1ec1n s\u1eed d\u1ee5ng ph\u00e2n t\u00edch di truy\u1ec1n.<\/p>\n<p style=\"text-align: justify;\">\u00a0\u00a0 V\u1ec1 ch\u1ee9c n\u0103ng (ho\u1ea1t \u0111\u1ed9ng) c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u, ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 VIII ho\u1eb7c y\u1ebfu t\u1ed1 IX trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng l\u00e0 100%. B\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng n\u1ebfu ho\u1ea1t \u0111\u1ed9ng d\u01b0\u1edbi 40%. Tuy nhi\u00ean, n\u1ebfu quan s\u00e1t th\u1ea5y ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 VIII gi\u1ea3m th\u00ec c\u1ea7n ph\u1ea3i x\u00e1c nh\u1eadn r\u1eb1ng kh\u00f4ng c\u00f3 s\u1ef1 b\u1ea5t th\u01b0\u1eddng n\u00e0o v\u1ec1 y\u1ebfu t\u1ed1 von Willebrand, b\u1edfi v\u00ec n\u1ed3ng \u0111\u1ed9 y\u1ebfu t\u1ed1 VIII c\u0169ng c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m trong b\u1ec7nh von Willebrand.<\/p>\n<p style=\"text-align: justify;\">\u00a0\u00a0 M\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng c\u0169ng \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh b\u1edfi m\u1ee9c \u0111\u1ed9 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u.<\/p>\n<p style=\"text-align: justify;\">\u00a0\u00a0 M\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng<\/p>\n<p style=\"text-align: justify;\">B\u1ec7nh n\u1eb7ng: Gi\u00e1 tr\u1ecb th\u1ea5p nh\u1ea5t sau nhi\u1ec1u l\u1ea7n ki\u1ec3m tra ho\u1ea1t \u0111\u1ed9ng \u0111\u00f4ng m\u00e1u d\u01b0\u1edbi 1%<\/p>\n<p style=\"text-align: justify;\">Trung b\u00ecnh: Gi\u00e1 tr\u1ecb \u0111\u00e1y ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u t\u1eeb 1% tr\u1edf l\u00ean nh\u01b0ng d\u01b0\u1edbi 5%<\/p>\n<p style=\"text-align: justify;\">Tri\u1ec7u ch\u1ee9ng nh\u1eb9: Gi\u00e1 tr\u1ecb \u0111\u00e1y ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u 5% tr\u1edf l\u00ean 2 (Gi\u1edbi h\u1ea1n tr\u00ean l\u00e0 40%)<\/p>\n<p style=\"text-align: justify;\">X\u00e9t nghi\u1ec7m di truy\u1ec1n s\u1eed d\u1ee5ng ph\u00e2n t\u00edch di truy\u1ec1n c\u00f3 s\u1eb5n \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh \u0111\u00e1ng tin c\u1eady.<\/p>\n<p style=\"text-align: justify;\">\u3000X\u00e9t nghi\u1ec7m di truy\u1ec1n ch\u1ec9 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u1edf m\u1ed9t s\u1ed1 \u00edt b\u1ec7nh vi\u1ec7n c\u00f3 th\u1ec3 ti\u1ebfn h\u00e0nh nghi\u00ean c\u1ee9u \u0111\u1eb7c bi\u1ec7t v\u00e0 c\u1ea7n c\u00f3 s\u1ef1 h\u1ee3p t\u00e1c c\u1ee7a c\u00e1c th\u00e0nh vi\u00ean trong gia \u0111\u00ecnh m\u1eafc b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng n\u00ean hi\u1ec7n nay vi\u1ec7c th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m di truy\u1ec1n kh\u00f4ng h\u1ec1 d\u1ec5 d\u00e0ng.<\/p>\n<p style=\"text-align: justify;\">\u3000Ph\u00e2n t\u00edch DNA theo ph\u1ea3n \u1ee9ng chu\u1ed7i polymerase (PCR) bao g\u1ed3m gen c\u1ee7a y\u1ebfu t\u1ed1 VIII ho\u1eb7c y\u1ebfu t\u1ed1 IX, c\u00f3 s\u1eb5n t\u1ea1i c\u00e1c trung t\u00e2m chuy\u00ean khoa, c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n tr\u1ea1ng th\u00e1i mang m\u1ea7m b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng A ho\u1eb7c B v\u00e0 ch\u1ea9n \u0111o\u00e1n tr\u01b0\u1edbc sinh v\u1ec1 b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng A ho\u1eb7c B b\u1eb1ng c\u00e1ch l\u1ea5y m\u1eabu l\u00f4ng nhung m\u00e0ng \u0111\u1ec7m \u1edf th\u1eddi \u0111i\u1ec3m 12 tu\u1ea7n ho\u1eb7c ch\u1ecdc \u1ed1i \u1edf th\u1eddi \u0111i\u1ec3m 16 tu\u1ea7n. Th\u1ee7 thu\u1eadt n\u00e0y c\u00f3 0,5 \u0111\u1ebfn 1% nguy c\u01a1 s\u1ea9y thai. C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 DNA b\u00e0o thai t\u1ef1 do trong m\u00e1u m\u1eb9 \u0111\u00e3 cho th\u1ea5y tri\u1ec3n v\u1ecdng l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p kh\u00f4ng x\u00e2m l\u1ea5n \u0111\u1ec3 s\u00e0ng l\u1ecdc b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng.<\/p>\n<p style=\"text-align: justify;\">\n<p>T\u00e0i li\u1ec7u tham kh\u1ea3o:<\/p>\n<ol>\n<li>Hemophilia &#8211; C\u1ea9m nang MSD &#8211; Phi\u00ean b\u1ea3n d\u00e0nh cho chuy\u00ean gia<\/li>\n<li>B\u1ec7nh Hemophilia \u2013 B\u1ec7nh vi\u1ec7n Huy\u1ebft h\u1ecdc v\u00e0 truy\u1ec1n m\u00e1u<\/li>\n<li>\u0110i\u1ec1u tr\u1ecb d\u1ef1 ph\u00f2ng &#8211; hy v\u1ecdng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh hemophilia \u2013 B\u1ed9 y t\u1ebf, c\u1ed5ng th\u00f4ng tin \u0111i\u1ec7n t\u1eed<\/li>\n<li>\u8840\u53cb\u75c5\u306e\u691c\u67fbhttps:\/\/www.clubhaemophilia.jp\/about\/haemophilia\/examination.html<\/li>\n<\/ol>\n<p style=\"text-align: right;\">T\u00e1c gi\u1ea3: TS Tr\u1ea7n Th\u1ecb Thanh Huy\u1ec1n<\/p>\n<p style=\"text-align: right;\">Gi\u1ea3ng vi\u00ean khoa X\u00e9t Nghi\u1ec7m Y H\u1ecdc<\/p>\n<p style=\"text-align: right;\">\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<section class=\"veu_cta\" id=\"veu_cta-790\"><h1 class=\"cta_title\">TUY\u1ec2N SINH 2024<\/h1><div class=\"cta_body\"><div class=\"cta_body_image cta_body_image_right\"><a href=\"https:\/\/4pal.net\/tuyen-sinh\/thong-tin-tuyen-sinh-2023\/\" target=\"_blank\"><img width=\"750\" height=\"422\" src=\"https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner-750x422.jpg\" class=\"attachment-large size-large\" alt=\"\" srcset=\"https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner-750x422.jpg 750w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner-300x169.jpg 300w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner-768x432.jpg 768w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner-1536x864.jpg 1536w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner-320x180.jpg 320w, https:\/\/4pal.net\/wp\/wp-content\/uploads\/2022\/07\/Banner.jpg 1890w\" sizes=\"(max-width: 750px) 100vw, 750px\" \/><\/a><\/div><div class=\"cta_body_txt image_exist\">B\u1ea1n \u0111ang ch\u01b0a bi\u1ebft l\u1ef1a ch\u1ecdn ng\u00e0nh n\u00e0o ?\r<br \/>H\u00e3y li\u00ean h\u1ec7 v\u1edbi ch\u00fang t\u00f4i \u0111\u1ec3 \u0111\u01b0\u1ee3c h\u1ed7 tr\u1ee3 - t\u01b0 v\u1ea5n.\r<br \/>Hotline: 0869 809 088\r<br \/>Email: tuyensinh@4pal.net\r<br \/>\r<br \/>H\u1eb9n g\u1eb7p l\u1ea1i c\u00e1c b\u1ea1n t\u1ea1i THUV.\r<br \/><\/div><div class=\"cta_body_link\"><a href=\"https:\/\/4pal.net\/tuyen-sinh\/thong-tin-tuyen-sinh-2023\/\" class=\"btn btn-primary btn-block btn-lg\" target=\"_blank\">TH\u00d4NG TIN CHI TI\u1ebeT T\u1ea0I \u0110\u00c2Y<\/a><\/div><\/div><\/section><div class=\"veu_socialSet veu_socialSet-position-after veu_contentAddSection\"><script>window.twttr=(function(d,s,id){var js,fjs=d.getElementsByTagName(s)[0],t=window.twttr||{};if(d.getElementById(id))return t;js=d.createElement(s);js.id=id;js.src=\"https:\/\/platform.twitter.com\/widgets.js\";fjs.parentNode.insertBefore(js,fjs);t._e=[];t.ready=function(f){t._e.push(f);};return t;}(document,\"script\",\"twitter-wjs\"));<\/script><ul><li class=\"sb_facebook sb_icon\"><a href=\"\/\/www.facebook.com\/sharer.php?src=bm&u=https%3A%2F%2F4pal.net%2Fbenh-mau-kho-dong-hemophilia-va-xet-nghiem-chan-doan%2F&amp;t=B%E1%BB%86NH+M%C3%81U+KH%C3%93+%C4%90%C3%94NG+%28HEMOPHILIA%29+V%C3%80+X%C3%89T+NGHI%E1%BB%86M+CH%E1%BA%A8N+%C4%90O%C3%81N+%7C+Tr%C6%B0%E1%BB%9Dng+%C4%90%E1%BA%A1i+h%E1%BB%8Dc+Y+khoa+Tokyo+Vi%E1%BB%87t+Nam\" target=\"_blank\" onclick=\"window.open(this.href,'FBwindow','width=650,height=450,menubar=no,toolbar=no,scrollbars=yes');return false;\"><span class=\"vk_icon_w_r_sns_fb icon_sns\"><\/span><span class=\"sns_txt\">Facebook<\/span><span class=\"veu_count_sns_fb\"><\/span><\/a><\/li><\/ul><\/div>","protected":false},"excerpt":{"rendered":"<p>T\u1ea1i Vi\u1ec7t Nam, \u01b0\u1edbc t\u00ednh c\u00f3 tr\u00ean 6.200 ng\u01b0\u1eddi m\u1eafc hemophilia (b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng) v\u00e0 c\u00f3 kho\u1ea3ng tr\u00ean 60% ng\u01b0\u1eddi b\u1ec7nh \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n v\u00e0 \u0111i\u1ec1u tr\u1ecb. \u00a0 B\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng (Hemophilia) l\u00e0 g\u00ec? Hemophilia l\u00e0 m\u1ed9t b\u1ec7nh l\u00fd r\u1ed1i lo\u1ea1n \u0111\u00f4ng m\u00e1u do nguy\u00ean nh\u00e2n di truy\u1ec1n (t\u1eeb cha m\u1eb9 truy\u1ec1n l\u1ea1i \u0111\u1eddi sau). B\u1ec7nh nh\u00e2n d\u1ec5 b\u1ecb ch\u1ea3y m\u00e1u kh\u00f3 c\u1ea7m v\u00ec thi\u1ebfu h\u1ee5t y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u. C\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u c\u00f3 s\u1eb5n trong th\u00e0nh ph\u1ea7n huy\u1ebft t\u01b0\u01a1ng c\u1ee7a m\u00e1u, khi m\u1ea1ch m\u00e1u v\u1ee1, c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u \u0111\u01b0\u1ee3c k\u00edch ho\u1ea1t s\u1ebd t\u1ea1o m\u1ed9t chu\u1ed7i ph\u1ea3n \u1ee9ng \u0111\u1ec3 t\u1ea1o ra c\u1ee5c m\u00e1u \u0111\u00f4ng b\u00edt k\u00edn ch\u1ed7 v\u1ee1 c\u1ee7a m\u1ea1ch m\u00e1u ng\u0103n ch\u1ea3y m\u00e1u. C\u00f3 2 th\u1ec3 b\u1ec7nh: Hemophilia A &#8211; thi\u1ebfu y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u VIII, Hemophilia B &#8211; thi\u1ebfu y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u IX. M\u1ed9t khi mang thai, ng\u01b0\u1eddi m\u1eb9 mang gen Hemophilia c\u00f3 kh\u1ea3 n\u0103ng truy\u1ec1n gen cho \u0111\u1eddi sau. Trong tr\u01b0\u1eddng h\u1ee3p, n\u1ebfu gen X mang b\u1ec7nh truy\u1ec1n cho con trai th\u00ec con trai s\u1ebd b\u1ecb Hemophilia. N\u1ebfu truy\u1ec1n cho con g\u00e1i th\u00ec con g\u00e1i s\u1ebd mang gen Hemophilia. Bi\u1ec3u hi\u1ec7n b\u1ec7nh: Ng\u01b0\u1eddi b\u1ec7nh r\u1ea5t d\u1ec5 b\u1ecb ch\u1ea3y m\u00e1u do va ch\u1ea1m, ch\u1ea5n th\u01b0\u01a1ng ho\u1eb7c c\u00f3 th\u1ec3 ch\u1ea3y m\u00e1u t\u1ef1 nhi\u00ean. C\u00f3 th\u1ec3 ch\u1ea3y m\u00e1u \u1edf b\u1ea5t k\u1ef3 c\u01a1 quan n\u00e0o trong c\u01a1 th\u1ec3 nh\u01b0ng th\u01b0\u1eddng g\u1eb7p nh\u1ea5t l\u00e0 c\u01a1 v\u00e0 kh\u1edbp Ch\u1ea3y m\u00e1u trong c\u01a1, kh\u1edbp, th\u01b0\u1eddng g\u1eb7p nh\u1ea5t l\u00e0 g\u1ed1i, khu\u1ef7u, \u0111\u1ea7u g\u1ed1i, m\u1eaft c\u00e1 ch\u00e2n, h\u00f4ng l\u01b0ng, c\u01a1 th\u1eaft l\u01b0ng, c\u01a1 b\u1eafp ch\u00e2n g\u00e2y ra \u0111au, s\u01b0ng c\u1ee9ng v\u00e0 kh\u00f3 c\u1eed \u0111\u1ed9ng kh\u1edbp. N\u1ebfu b\u1ec7nh di\u1ec5n ti\u1ebfn l\u00e2u, c\u00f3 th\u1ec3 \u0111\u1ec3 l\u1ea1i di ch\u1ee9ng bi\u1ebfn d\u1ea1ng kh\u1edbp, gi\u1edbi h\u1ea1n v\u1eadn \u0111\u1ed9ng. B\u00e1o c\u00e1o \u201cTi\u1ebfp c\u1eadn \u0111i\u1ec1u tr\u1ecb b\u1ec7nh nh\u00e2n Hemophilia theo h\u01b0\u1edbng c\u00e1 th\u1ec3 h\u00f3a\u201d c\u1ee7a BS Nguy\u1ec5n Minh Tu\u1ea5n \u2013 Tr\u01b0\u1edfng khoa S\u1ed1t xu\u1ea5t huy\u1ebft, B\u1ec7nh vi\u1ec7n Nhi \u0111\u1ed3ng 1 t\u1ea1i Ch\u01b0\u01a1ng tr\u00ecnh h\u1ed9i th\u1ea3o khoa h\u1ecdc tr\u1ef1c tuy\u1ebfn nh\u1eb1m c\u1eadp nh\u1eadt ki\u1ebfn th\u1ee9c v\u00e0 trao \u0111\u1ed5i chuy\u00ean m\u00f4n trong c\u00f4ng t\u00e1c ch\u1ea9n \u0111o\u00e1n v\u00e0 qu\u1ea3n l\u00fd b\u1ec7nh nh\u00e2n Hemophilia n\u0103m 2023. \u00a0\u00a0 C\u00e1c x\u00e9t nghi\u1ec7m \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh hemophilia Hi\u1ec7n t\u1ea1i, c\u00f3 hai lo\u1ea1i ch\u1ea9n \u0111o\u00e1n ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh \u0111\u1ec3 x\u00e1c \u0111\u1ecbnh xem m\u1ed9t ng\u01b0\u1eddi c\u00f3 ph\u1ea3i l\u00e0 ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh hay kh\u00f4ng: x\u00e9t nghi\u1ec7m \u0111\u00f4ng m\u00e1u \u0111\u1ec3 \u0111o ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u v\u00e0 x\u00e9t nghi\u1ec7m di truy\u1ec1n s\u1eed d\u1ee5ng ph\u00e2n t\u00edch di truy\u1ec1n. \u00a0\u00a0 V\u1ec1 ch\u1ee9c n\u0103ng (ho\u1ea1t \u0111\u1ed9ng) c\u1ee7a c\u00e1c y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u, ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 VIII ho\u1eb7c y\u1ebfu t\u1ed1 IX trong huy\u1ebft t\u01b0\u01a1ng c\u1ee7a ng\u01b0\u1eddi b\u00ecnh th\u01b0\u1eddng l\u00e0 100%. B\u1ec7nh nh\u00e2n \u0111\u01b0\u1ee3c ch\u1ea9n \u0111o\u00e1n m\u1eafc b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng n\u1ebfu ho\u1ea1t \u0111\u1ed9ng d\u01b0\u1edbi 40%. Tuy nhi\u00ean, n\u1ebfu quan s\u00e1t th\u1ea5y ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 VIII gi\u1ea3m th\u00ec c\u1ea7n ph\u1ea3i x\u00e1c nh\u1eadn r\u1eb1ng kh\u00f4ng c\u00f3 s\u1ef1 b\u1ea5t th\u01b0\u1eddng n\u00e0o v\u1ec1 y\u1ebfu t\u1ed1 von Willebrand, b\u1edfi v\u00ec n\u1ed3ng \u0111\u1ed9 y\u1ebfu t\u1ed1 VIII c\u0169ng c\u00f3 th\u1ec3 b\u1ecb gi\u1ea3m trong b\u1ec7nh von Willebrand. \u00a0\u00a0 M\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng c\u0169ng \u0111\u01b0\u1ee3c x\u00e1c \u0111\u1ecbnh b\u1edfi m\u1ee9c \u0111\u1ed9 ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u. \u00a0\u00a0 M\u1ee9c \u0111\u1ed9 nghi\u00eam tr\u1ecdng c\u1ee7a b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng B\u1ec7nh n\u1eb7ng: Gi\u00e1 tr\u1ecb th\u1ea5p nh\u1ea5t sau nhi\u1ec1u l\u1ea7n ki\u1ec3m tra ho\u1ea1t \u0111\u1ed9ng \u0111\u00f4ng m\u00e1u d\u01b0\u1edbi 1% Trung b\u00ecnh: Gi\u00e1 tr\u1ecb \u0111\u00e1y ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u t\u1eeb 1% tr\u1edf l\u00ean nh\u01b0ng d\u01b0\u1edbi 5% Tri\u1ec7u ch\u1ee9ng nh\u1eb9: Gi\u00e1 tr\u1ecb \u0111\u00e1y ho\u1ea1t \u0111\u1ed9ng c\u1ee7a y\u1ebfu t\u1ed1 \u0111\u00f4ng m\u00e1u 5% tr\u1edf l\u00ean 2 (Gi\u1edbi h\u1ea1n tr\u00ean l\u00e0 40%) X\u00e9t nghi\u1ec7m di truy\u1ec1n s\u1eed d\u1ee5ng ph\u00e2n t\u00edch di truy\u1ec1n c\u00f3 s\u1eb5n \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n ng\u01b0\u1eddi mang m\u1ea7m b\u1ec7nh \u0111\u00e1ng tin c\u1eady. \u3000X\u00e9t nghi\u1ec7m di truy\u1ec1n ch\u1ec9 \u0111\u01b0\u1ee3c th\u1ef1c hi\u1ec7n \u1edf m\u1ed9t s\u1ed1 \u00edt b\u1ec7nh vi\u1ec7n c\u00f3 th\u1ec3 ti\u1ebfn h\u00e0nh nghi\u00ean c\u1ee9u \u0111\u1eb7c bi\u1ec7t v\u00e0 c\u1ea7n c\u00f3 s\u1ef1 h\u1ee3p t\u00e1c c\u1ee7a c\u00e1c th\u00e0nh vi\u00ean trong gia \u0111\u00ecnh m\u1eafc b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng n\u00ean hi\u1ec7n nay vi\u1ec7c th\u1ef1c hi\u1ec7n x\u00e9t nghi\u1ec7m di truy\u1ec1n kh\u00f4ng h\u1ec1 d\u1ec5 d\u00e0ng. \u3000Ph\u00e2n t\u00edch DNA theo ph\u1ea3n \u1ee9ng chu\u1ed7i polymerase (PCR) bao g\u1ed3m gen c\u1ee7a y\u1ebfu t\u1ed1 VIII ho\u1eb7c y\u1ebfu t\u1ed1 IX, c\u00f3 s\u1eb5n t\u1ea1i c\u00e1c trung t\u00e2m chuy\u00ean khoa, c\u00f3 th\u1ec3 \u0111\u01b0\u1ee3c s\u1eed d\u1ee5ng \u0111\u1ec3 ch\u1ea9n \u0111o\u00e1n tr\u1ea1ng th\u00e1i mang m\u1ea7m b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng A ho\u1eb7c B v\u00e0 ch\u1ea9n \u0111o\u00e1n tr\u01b0\u1edbc sinh v\u1ec1 b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng A ho\u1eb7c B b\u1eb1ng c\u00e1ch l\u1ea5y m\u1eabu l\u00f4ng nhung m\u00e0ng \u0111\u1ec7m \u1edf th\u1eddi \u0111i\u1ec3m 12 tu\u1ea7n ho\u1eb7c ch\u1ecdc \u1ed1i \u1edf th\u1eddi \u0111i\u1ec3m 16 tu\u1ea7n. Th\u1ee7 thu\u1eadt n\u00e0y c\u00f3 0,5 \u0111\u1ebfn 1% nguy c\u01a1 s\u1ea9y thai. C\u00e1c nghi\u00ean c\u1ee9u v\u1ec1 DNA b\u00e0o thai t\u1ef1 do trong m\u00e1u m\u1eb9 \u0111\u00e3 cho th\u1ea5y tri\u1ec3n v\u1ecdng l\u00e0 m\u1ed9t ph\u01b0\u01a1ng ph\u00e1p kh\u00f4ng x\u00e2m l\u1ea5n \u0111\u1ec3 s\u00e0ng l\u1ecdc b\u1ec7nh m\u00e1u kh\u00f3 \u0111\u00f4ng. T\u00e0i li\u1ec7u tham kh\u1ea3o: Hemophilia &#8211; C\u1ea9m nang MSD &#8211; Phi\u00ean b\u1ea3n d\u00e0nh cho chuy\u00ean gia B\u1ec7nh Hemophilia \u2013 B\u1ec7nh vi\u1ec7n Huy\u1ebft h\u1ecdc v\u00e0 truy\u1ec1n m\u00e1u \u0110i\u1ec1u tr\u1ecb d\u1ef1 ph\u00f2ng &#8211; hy v\u1ecdng c\u1ee7a ng\u01b0\u1eddi b\u1ec7nh hemophilia \u2013 B\u1ed9 y t\u1ebf, c\u1ed5ng th\u00f4ng tin \u0111i\u1ec7n t\u1eed \u8840\u53cb\u75c5\u306e\u691c\u67fbhttps:\/\/www.clubhaemophilia.jp\/about\/haemophilia\/examination.html T\u00e1c gi\u1ea3: TS Tr\u1ea7n Th\u1ecb Thanh Huy\u1ec1n Gi\u1ea3ng vi\u00ean khoa X\u00e9t Nghi\u1ec7m Y H\u1ecdc &nbsp; &nbsp; &nbsp;<\/p>\n","protected":false},"author":18,"featured_media":11422,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_monsterinsights_skip_tracking":false,"_monsterinsights_sitenote_active":false,"_monsterinsights_sitenote_note":"","_monsterinsights_sitenote_category":0,"_uf_show_specific_survey":0,"_uf_disable_surveys":false,"footnotes":""},"categories":[144,123,160],"tags":[],"class_list":["post-11420","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-cam-nang","category-khac","category-nhat-ky-giang-vien"],"_links":{"self":[{"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/posts\/11420"}],"collection":[{"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/users\/18"}],"replies":[{"embeddable":true,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/comments?post=11420"}],"version-history":[{"count":1,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/posts\/11420\/revisions"}],"predecessor-version":[{"id":11423,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/posts\/11420\/revisions\/11423"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/media\/11422"}],"wp:attachment":[{"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/media?parent=11420"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/categories?post=11420"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/4pal.net\/wp-json\/wp\/v2\/tags?post=11420"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}